Instrument families
OpenSXRaw's corpus covers two SCIEX instrument families that both use the
legacy .wiff/.wiff.scan container:
TripleTOF
Quadrupole time-of-flight instruments (TripleTOF 5600/6600 confirmed in
the validation corpus). TripleTOF acquisitions run high-resolution
DDA (data-dependent acquisition) or DIA/SWATH workflows, and make heavy
use of TOF-specific calibration telemetry (TOFCalibrationData,
TDCStatistics) and ExperimentTOF method blocks - see
Format specification.
QTRAP
Triple-quadrupole linear ion trap instruments (QTRAP 5500/6500 confirmed
in the validation corpus) typically running scheduled MRM/SRM targeted
acquisitions (sMRM/sMRMEX method blocks). QTRAP is nominal-mass, not
true time-of-flight, unlike TripleTOF.
How the reader tells them apart
It currently doesn't. Reader reads scan data identically for both
families via the shared Idx/.wiff.scan mechanism, and reports every
spectrum with the same Analyzer::TOFMS / profile-mode metadata
regardless of source instrument - see
Reader: what the reader does not yet do.
If you need to distinguish TripleTOF from QTRAP output today, check the
method-subtree contents yourself (ExperimentTOF vs sMRM/sMRMEX) - a
proper instrument-family detector is not yet built into the reader API.